Members

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Research Focus

We collaborate closely with the Department of Neurosurgery to establish cell lines and xenograft models from resected brain tumor tissue. By developing brain tumor models that faithfully recapitulate the original tumor and by collaborations both inside Japan and abroad, we aim to elucidate the pathophysiology and resistance mechanisms of rare brain tumors. Treatments are not restricted to chemotherapy and radiation but also include molecularly targeted therapy, epigenetic modifiers, and photoimmunotherapy.

We have now just assembled a new team and will strive to tackle new projects, including elucidating the pathophysiology of neural regeneration, assessing plasticity in the epileptic brain, and visualization of glioma-neuron interaction. We will also collaborate with other Departments inside the Brain Research Institute to answer complex problems using state-of-the-art techniques.