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Members

Prof.
Makoto OISHI

Assoc. Prof.
Hitoshi HASEGAWA


Lecturer
Tetsuya HIRAISHI

Assist. Prof.
Tomoaki SUZUKI

Assist. Prof.
Yoshihiro TSUKAMOTO

Assist. Prof.
Daijyu MITSUHASHI

Clinical Assist. Prof.
Satoshi SHIBUMA

Clinical Assist. Prof.
Hidemoto FUJIWARA

Clinical Assist. Prof.
Shisei YOSHIDA

Specially Appointed Prof.
Yuichiro YONEOKA

Specially Appointed Lecturer.
Haruhiko TAKAHASHI

Specially Appointed Assist. Prof.
Ryousuke OGURA


Specially Appointed Assoc. Prof.
(Advanced Treatment of
Neurological Diseases Branch)
Manabu NATSUMEDA

Research Focus

Department of Neurosurgery, University of Niigata was founded by Professor Mizuho Nakata, "the father of Neurosurgery in Japan", in 1953, becoming the first independent Department of Neurosurgery in Japan. Since then, the department has led the field of preclinical research and surgery for brain tumors, cerebral vascular disease, brain trauma, and functional surgery. Also, the department is unique in that it is affiliated with the Brain Research Institute, enabling collaboration with many basic neuroscience laboratories within the Institute. Answering clinical questions through basic research and using the results to improve clinical medicine, is precisely what Professor Nakata envisioned when he founded the Brain Research Institute. It is our obligation to carry on this spirit, and all staff is dedicated to discovering new insight into neurosurgical practice. Dr. Makoto Oishi has been appointed as the 5th professor of the Department of Neurosurgery, Niigata University since June 2023, and we will continue to proudly develop our historic department for further clinical and research development. The main research areas we are currently focusing on include: (1)establishing brain tumor cell lines and intracranial xenografts to develop the best strategies to treat each tumor, (2) diagnosing brain tumors by detecting driver mutations from cell-free DNA of cerebrospinal fluid, (3) inventing marker to detect venous thromboembolism in glioma , (4) identifying molecular makers of human axonal regeneration and development, (5) developing assistive surgical technology to enable accurate simulation for complex neurosurgery cases and education of young neurosurgeons, (6) collaboration with Nishi-Niigata Chuo National Hospital to elucidate the complex pathophysiology of epilepsy using flavoprotein fluorescence imaging.



Fig 1. C2PAC index in patients with venous thromboembolism (VTE) and without VTE in patients with isocitrate dehydrogenase (IDH)-wildtype gliomas.

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