PNAS published a Commentary on our APP study
PNAS has published a Commentary on our recent paper describing a role for APP in clearing nuclear-derived waste.
Thangavel M, Masurkar AV. Nuclear garbage disposal: An unexpected role for amyloid precursor protein in Alzheimer’s disease. Proc. Natl. Acad. Sci. USA. 2026;123(32):e2619791123.
https://doi.org/10.1073/pnas.2619791123
Original article: Dougnon G, et al. A protective role for APP in nuclear waste clearance via lysosomal exocytosis. Proc. Natl. Acad. Sci. USA. 2026;123(24):e2524190123.