Publications

 

 

 

 

2020
Netrin-G1 regulates microglial accumulation along axons and supports the survival of layer V neurons in the postnatal mouse brain.
Fujita Y, Nakanishi T, Ueno M, Itohara S, Yamashita T. 
Cell Rep 31(4): 107580, 2020
 
Inhibition of HDAC increases BDNF expression and promotes neuronal rewiring and functional recovery after brain injury.
Sada N, Fujita Y, Mizuta N, Ueno M, Furukawa T, Yamashita T. 
Cell Death Dis 11: 655, 2020
 
Olig2-induced semaphorin expression drives corticospinal axon retraction after spinal cord injury.
*#Ueno M, #Nakamura Y, Nakagawa H, Niehaus JK, Maezawa M, Gu Z, Kumanogoh A, Takebayashi H, Lu QR, Takada M, Yoshida Y. 
Cereb Cortex  30(11): 5702-5716, 2020
 
Ghrelin-insulin-like growth factor-1 axis is activated via autonomic neural circuits in the non-alcoholic fatty liver disease.
Nagoya T, Kamimura K, Inoue R, Ko M, Owaki T, Niwa Y, Sakai N, Setsu T, Sakamaki A, Yokoo T, Kamimura H, Nakamura Y, Ueno M, Terai S. 
Neurogastroenterol Motil  32(5): e13799, 2020
 
Combinational approach of genetic SHP-1 suppression and voluntary exercise promotes corticospinal tract sprouting and motor recovery following brain injury.
Tanaka T, Ito T, Sumizono M, Ono M, Kato N, Honma S, Ueno M. 
Neurorehabil Neural Repair 34(6): 558-70, 2020
 
Direct comparison of odor responses of homologous glomeruli in the medial and lateral maps of the mouse olfactory bulb.
Sato T, Homma R, Nagayama S. 
eNeuro  0449-19, 2020 
 
動きを生み出す脳の仕組みと謎
上野将紀

 
中枢神経障害による神経回路の再編と機能回復
上野将紀
新潟医学会雑誌．134(1): 7–12, 2020 
 
随意運動をになう神経回路の再建 〜基礎研究の現状と課題〜
上野将紀
新潟県医師会報．842: 2–7, 2020 

 

2019
Skilled movements in mice require inhibition of corticospinal axon collateral formation in the spinal cord by semaphorin signaling.
Gu Z, Ueno M, Klinefelter K, Mamidi M, Yagi T, Yoshida Y.
J Neurosci 39: 8885-99, 2019
 
Dual functions of microglia in the formation and refinement of neural circuits during development.
Konishi H, Kiyama H, *Ueno M.
Int J Dev Neurosci  77: 18-25, 2019
 
脊髄損傷と自律神経-臓器-免疫連関
上野将紀

 

 

2018 
Corticospinal circuits from the sensory and motor cortices differentially regulate skilled movements through distinct spinal interneurons.
*Ueno M, Nakamura Y, Li J, Gu Z, Niehaus J, Maezawa M, Crone SA, Goulding M, Baccei ML, Yoshida Y.
Cell Reports 23: 1286-1300, 2018 　
https://www.sciencedirect.com/science/article/pii/S2211124718305254?via%3Dihub

     新潟日報朝刊（2018年5月15日）、科学新聞（2018年5月25日）に掲載
 
MARCKSL1 regulates spine formation in the amygdala and controls the hypothalamic-pituitary-adrenal axis and anxiety-like behaviors.
Tanaka T, Shimizu S, Ueno M, Fujihara Y, Ikawa M, Miyata S.
EBioMedicine 30: 62-73, 2018
 
脳・脊髄の障害による神経‒免疫制御システムの破綻
上野将紀

 

 

2016  
Silencing spinal interneurons inhibits immune suppressive autonomic reflexes caused by spinal cord injury. 
Ueno M, Ueno-Nakamura Y, Niehaus J, Popovich PG, Yoshida Y.
Nat Neurosci. 19(6):784-7, 2016

 

    実験医学（羊土社）、にて紹介

 
脊髄損傷後の自律神経回路の再編成による免疫機能低下のメカニズム
上野将紀、Phillip Popovich、吉田富
実験医学．羊土社．34(14), 2328-31, 2016 

 

2015 
The brain-immune network in spinal cord injury.
*Ueno M, Yamashita T.
Neurodegenerative Disorder as Systematic Diseases. Wada K (Ed.), Springer, 41­–66, 2015

 

2014 
A selector orchestrates cortical function.
Ueno M, Fujiki R, Yamashita T. 
Nat Neurosci. 17(8):1016-7, 2014
 
Bidirectional tuning of microglia in the developing brain: from neurogenesis to neural circuit formation.
*Ueno M, Yamashita T. 
Curr Opin Neurobiol. 27C 8-15, 2014

 

2013 
Layer V cortical neurons require microglial support for survival during postnatal development.
*Ueno M, Fujita Y, Tanaka T, Nakamura Y, Kikuta J, Ishii M, Yamashita T. 
Nat Neurosci. 16(5): 543-551, 2013
　　Thomson Reuters社Web of ScienceにてHighly Cited Paper

 
Bilateral movement training promotes axonal remodeling of the corticospinal tract and recovery of motor function following traumatic brain injury in mice.
Nakagawa H, Ueno M, Itokazu T, Yamashita T. 
Cell Death Dis. 4: e534, 2013
 
Suppression of SHP-1 promotes corticospinal tract sprouting and functional recovery after brain injury.
Tanaka T, Fujita Y, Ueno M, Shultz LD, Yamashita T. 
Cell Death Dis. 4: e567, 2013   
 
IFN-γ-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injury.
Ishii H, Tanabe S, Ueno M, Kubo T, Kayama H, Serada S, Fujimoto M, Takeda K, Naka T, Yamashita T.
Cell Death Dis. 4 e710, 2013    
 
Soluble β-amyloid precursor protein alpha binds to p75 neurotrophin receptor to promote neurite outgrowth.
Hasebe N, Fujita Y, Ueno M, Yoshimura K, Fujino Y, Yamashita T.
PLoS One.  8 e82321, 2013  
 
脳発達期においてミクログリアは大脳皮質第５層神経細胞の生存に寄与する．
上野将紀、藤田幸、山下俊英:

 
研コミュ白書 第9回 UC-Tomorrow: シンシナティから発する明日のサイエンスへの光­―遥かなる上を目指して―．
山田宗茂、合山進、上野将紀、佐々木敦朗．
細胞工学．学研メディカル秀潤社．32(11) 1174-7, 2013

  

2012
Intraspinal rewiring of the corticospinal tract requires target-derived BDNF and compensates lost function after brain injury.
Ueno M, Hayano Y, Nakagawa, H, Yamashita T. 
Brain.135(4): 1253-67, 2012
   NHKテレビ「おはよう関西」にて紹介（2012年4月3日）
   時事通信（2012年4月2日）、読売新聞朝刊（2012年4月4日）に掲載

 
Adoptive transfer of Th1-conditioned lymphocytes promotes axonal remodeling and functional recovery after spinal cord injury.
Ishii H, Jin X, Ueno M, Tanabe S, Kubo T, Serada S, Naka T, Yamashita T.
Cell Death Dis. 3: e363, 2012
 
Activated microglia inhibit axonal growth through RGMa.
Kitayama M, Ueno M, Itakura T, Yamashita T.
PLoS One. 6(9): e25234, 2011.

 

2011 
Kinematic analyses reveal impaired locomotion following injury of the motor cortex in mice.
*Ueno M, Yamashita T. 
Exp Neurol. 230(2): 280-90, 2011
 
Paired immunoglobulin-like receptor B knockout does not enhance axonal regeneration or locomotor recovery after spinal cord injury.
Nakamura Y, Fujita Y, Ueno M, Takai T, Yamashita T. 
J Biol Chem. 286(3): 1876-83, 2011
 
Axonal remodeling for motor recovery after traumatic brain injury requires downregulation of  g-aminobutyric acid signaling.
Lee S, Ueno M, Yamashita T. 
Cell Death Dis. 2: e133, 2011
 
Dynamic spatiotemporal gene expression in embryonic mouse thalamus.
Suzuki-Hirano A, Ogawa M, Kataoka A, Yoshida AC, Itoh D, Ueno M, Blackshaw S, Shimogori T. 
J Comp Neurol. 519(3): 528-43, 2011
  
Corticospinal tract fibers cross the ephrin-B3-negative part of the midline of the spinal cord after brain injury.
Omoto S, Ueno M, Mochio S, Takai T, Yamashita T.
Neurosci Res. 69(3):187-95, 2011
 
C-Jun N-terminal kinase induces axonal degeneration and limits motor recovery after spinal cord injury in mice.
Yoshimura K, *Ueno M, Lee S, Nakamura Y, Sato A, Yoshimura K, Kishima H, Yoshimine T, Yamashita T. 
Neurosci Res. 71(3): 266-77, 2011
 
RhoA activation and effect of Rho-kinase inhibitor in the development of retinal neovascularization in a mouse model of oxygen-induced retinopathy.
Fang X, Ueno M, Yamashita T, Ikuno Y.
Curr Eye Res. 36(11): 1028-36, 2011

 

2010 
Genetic deletion of paired immunoglobulin-like receptor B does not promote axonal plasticity or functional recovery after traumatic brain injury.
Omoto S, Ueno M, Mochio S, Takai T, Yamashita T.
J Neurosci. 30(39): 13045-52, 2010
 
Expression of galectin-1 in immune cells and glial cells after spinal cord injury.
Kurihara D, Ueno M, Tanaka T, Yamashita T.
Neurosci Res. 66(3): 265-270, 2010
 
Olfactory mucosa transplantation following spinal cord injury improves voiding efficiency by suppressing detrusor sphincter dyssynergia in rats.
Nakayama J, Takao T, Kiuchi H, Yamamoto K, Fukuhara S, MiyagawaY, Aoki M, Iwatsuki K, Yoshimine T, Ueno M, Yamashita T, Nonomura N, Tsujimura A, Okuyama A.
J Urol. 184(2): 775-82, 2010
 
Transplantation of whole-layer olfactory mucosa promotes restricted functional recovery in rats with complete spinal cord injury.
Aoki M, Kishima H, Yoshimura Y, Ishihara M, Ueno M, Hata K, Yamashita T, Iwatsuki K, Yoshimine T.
J Neurosurg: Spine. 12(2): 122-30, 2010

 

2009
Engulfment of axon debris by microglia requires p38 MAPK activity.
Tanaka T, Ueno M, Yamashita T. 
J Biol Chem. 284(32): 21626-36, 2009
 
Etoposide induces TRP53-dependent apoptosis and TRP53-independent cell-cycle arrest in trophoblasts of the developing mouse placenta.
Yamauchi H, Katayama KI, Ueno M, Kanemitsu H, Nam C, Mikami T, Saito A, Ishida Y, Uetsuka K, Doi K, Ohmach Y, Nakayama H.
Biol Reprod. 80(4): 813-22, 2009
 
Intrinsic regenerative mechanisms of central nervous system neurons. 
Muramatsu R, Ueno M, Yamashita T. 
Biosci Trends. 3(5): 179-183, 2009

 

2008 
Regulation of axonal elongation and pathfinding from the entorhinal cortex to the dentate gyrus in the hippocampus by the chemokine stromal cell-derived factor 1a.
Ohshima Y, Kubo T, Koyama R, Ueno M, Nakagawa M, Yamashita, T. 
J Neurosci. 28(33): 8344-53, 2008
 
Strategies for regenerating injured axons after spinal cord injury-insights from brain development.
*Ueno M, and Yamashita T. 
Biologics. 2(2): 253-64, 2008

 

2007 
Essential role of p53 in trophoblastic apoptosis induced in the developing rodent placenta by treatment with a DNA-damaging agent.
Yamauchi H, Katayama K, Ueno M, He XJ, Mikami T, Uetsuka K, Doi K, Nakayama H. 
Apoptosis. 12(10): 1743-54, 2007
 
Gene expression profiles of drug-metabolizing enzymes (DMEs) in rat liver during pregnancy and lactation.
He XJ, Yamauchi H, Suzuki K, Ueno M, Nakayama H, Doi K. 
Exp Mol Pathol. 83(3): 428-34, 2007

 

2006 
Cell cycle and cell death regulation of neural progenitor cells in the 5-azacytidine (5AzC)-treated developing fetal brain.
*Ueno M, Katayama K, Yamauchi H, Nakayama H, Doi K.
Exp Neurol. 198(1): 154-66, 2006
 
Repair process of fetal brain after 5-azacytidine-induced damage.
*Ueno M, Katayama K, Yamauchi H, Yasoshima A, Nakayama H, Doi K. 
Eur J Neurosci. 24(10): 2758-68, 2006
 
Cell cycle progression is required for nuclear migration of neural progenitor cells.
*Ueno M, Katayama K, Yamauchi H, Nakayama H, Doi K. 
Brain Res. 1088(1): 57-67, 2006
     総説Ann Rev Neurosci 32: 149-84 (2009), Neuron 67: 906-14 (2010)
     教科書「脳の発生学：ニューロンの誕生・分化・回路形成（化学同人社2013）」 等にて引用.
 
Evidence of apoptosis in the subventricular zone and rostral migratory stream in the MPTP mouse model of Parkinson disease.
He XJ, Nakayama H, Dong M, Yamauchi H, Ueno M, Uetsuka K, Doi K. 
J Neuropathol Exp Neurol. 65(9): 873-82, 2006

 

2005
Ethylnitrosourea induces neural progenitor cell apoptosis after S-phase accumulation in a p53-dependent manner.
Katayama K, Ueno M, Yamauchi H, Nagata T, Nakayama H, Doi K. 
Neurobiol Dis. 18(1): 218-25, 2005
 
Microarray analysis of genes in fetal central nervous system after ethylnitrosourea administration.
Katayama K, Ueno M, Yamauchi H, Nakayama H, Doi K.
Birth Defects Res B Dev Reprod Toxicol. 74(3): 255-60, 2005

 

2004
Involvement of p53 in 1-beta-D-arabinofuranosylcytosine-induced trophoblastic cell apoptosis and impaired proliferation in rat placenta.
Yamauchi H, Katayama K, Ueno M, Uetsuka K, Nakayama H, Doi K. 
Biol Reprod. 70(6): 1762-7, 2004
 
Involvement of p53 in 1-beta-D-arabinofuranosylcytosine-induced rat fetal brain lesions.
Yamauchi H, Katayama K, Ueno M, Uetsuka K, Nakayama H, Doi K. 
Neurotoxicol Teratol. 26(4): 579-86, 2004
 
Effects of prenatal hydroxyurea-treatment on mouse offspring.
Woo GH, Katayama K, Bak EJ, Ueno M, Yamauchi H, Uetsuka K, Nakayama H, Doi K.
Exp Toxicol Pathol. 56(1-2): 1-7, 2004 

 

2002
Mechanisms of 5-azacytidine (5AzC)-induced toxicity in the rat foetal brain.
*Ueno M, Katayama K, Nakayama H, Doi K. 
Int J Exp Pathol. 83(3): 139-50, 2002
 
5-Azacytidine (5AzC)-induced histopathological changes in the central nervous system of rat fetuses.
*Ueno M, Katayama K, Yasoshima A, Nakayama H, Doi K. 
Exp Toxicol Pathol. 54(2): 91-6, 2002
 
Expression of ribosomal protein L4 (rpL4) during neurogenesis and 5-azacytidine (5AzC)-induced apoptotic process in the rat.
*Ueno M, Nakayama H, Kajikawa S, Katayama K, Suzuki K, Doi K. 
Histol Histopathol. 17(3): 789-98, 2002
 
Ethylnitrosourea induces apoptosis and growth arrest in the trophoblastic cells of rat placenta.
Katayama K, Ueno M, Takai H, Ejiri N, Uetsuka K, Nakayama H, Doi K. 
Biol Reprod. 67(2): 431-5, 2002
 
Ethylnitrosourea-induced apoptosis in primordial germ cells of the rat fetus.
Katayama K, Ueno M, Yamauchi H, Nakayama H, Doi K. 
Exp Toxicol Pathol. 54(3): 193-6, 2002