Our lab studies connectivity and functions of neural circuits in normal and injured brain/spinal cord. NEWS 2025.07.15 New Yoshino won the Yujin Memorial Medical Student Research Award! 2025.07.06 New We joined the Gordon Research Conference (@ Lucca). 2025.06.29 New Shoji won the Yujin Memorial Award! 2025.06.19 New Taka introduced the studies of BDNF and exercize in Tarzan. 2025.06.09 New A review article (in Japanese): Approaches for inducing neural plasticity via targeting inhibitory circuits after stroke. Inoue T, Ueno M. Med Sci Dig 51(7): 74-76, 2025 2025.06.06 New Hideki's paper in Neurobiol Dis: TDP-43 mutants with different aggregation properties exhibit distinct toxicity, axonal transport, and secretion for disease progression in a mouse ALS/FTLD model. Mori H, Sato T, Tsuboguchi S, Takahashi M, Nakamura Y, Hoshina K, Kato T, Fujii M, Onodera O, Ueno M. Neurobiol Dis. 212: 106988, 2025 2025.04.02 New Rie has joined our lab! 2025.03.21 New Taka's review: The diversity and plasticity of descending motor pathways rewired after stroke and trauma in rodents. Inoue T, Ueno M. Front Neural Circuits 19: 1566562, 2025 2025.03.19 New Yoshino won the Undergraduate Poster Award at the APPW2025! 2025.03.15 New Presentations in several meetings in March. 2025.03.12 New Poster presentation at the Spinal cord formation, function, and beyond @ OIST 2025.02.05 New The 14th NIPS-BRI-EHUB Joint Symposium. 2025.01.22 New Toki's preprint in bioRxiv: Scg2 drives reorganization of the corticospinal circuit with spinal premotor interneurons to recover motor function after stroke. Sato T, Nakamura Y, Hoshina K, Inoue KI, Takada M, Yano M, Matsuzawa H, Ueno M. bioRxiv 2025 2025.01.11 New Yoshino won the Best Student Presentation Award at the 11th Niigata-Juntendo University Joint Seminar! 2024.12.17 New We joined the 2nd Brain Repair Meeting (@Tokyo). 2024.11.27 New Invited talk at the 47th Annual Meeting of the Molecular Biology Society of Japan (@ Fukuoka). 2024.11.22 New Shoji's paper in JCI Insight: CRISPR/CasRx suppresses KRAS-induced brain arteriovenous malformation developed in postnatal brain endothelial cells in mice. Saito S, Nakamura Y, Miyashita S, Sato T, Hoshina K, Okada M, Hasegawa H, Oishi M, Fujii Y, Körbelin J, Kubota Y, Tainaka K, Natsumeda M, Ueno M. JCI Insight 9: e179729, 2024 2024.11.13 New We hold a seminar at BRI. 2024.11.11 New Reina has joined our lab! 2024.10.21 New A review article (in Japanese): Rehabilitation to restore neural repair capacity in the aged brain. Tanaka T, Ueno M. Med Sci Dig 50(12): 602-604, 2024 2024.10.12 New Invited talk at the 29th meeting of Japanese Society of Physical Therapy (@ Hachioji). 2024.10.02 New A review article (in Japanese): Elucidating the neural network of cerebrospinal fluid-contacting neurons. Nakamura Y, Ueno M. Seitai No Kagaku 75(5): 406-7, 2024 2024.09.19 New Invited talk at the QSLSL/IUSNA symposium. 2024.09.09 New Yuki has joined our lab! 2024.09.06 New Shintaro's paper was awarded the excellent papers in our university! 2024.08.17 New Yoshino presneted a poster at the 14th Summer Retreat in East Japan Basic Medical Training Program Consortium. 2024.07.25 New Wenbo (Harbin Med Univ) is joining our lab in the Summer Medical Exchange Program. 2024.07.16 New BRI is recruiting associate professor position (tenure track). 2024.07.13 New Presentation at the 64th Niigata biochemistry meeting @ Niigata 2024.06.07 New Invited talk at the National Center of Neurology and Psychiatry (NCNP). 2024.05.22 New A review article (in Japanese): Rewiring of the corticospinal circuit and the molecular mechanism after stroke. Sato T, Ueno M. Med Sci Dig 50(6): 48-50, 2024 2024.05.10 New We hold a seminar at BRI. 2024.05.02 New Moeka has joined our lab! 2024.05.01 New A review article (in Japanese): Protein spreading in ALS: disease progression by TDP-43 in the motor circuits. Tsuboguchi S, Onodera O, Ueno M. Farumashia 60(5): 393-397, 2024 (in Japanese) 2024.04.15 New Selected as the best paper in 2023 in J Phys Ther Fund. 2024.03.15 New Invited talks in several meetings in March. 2024.03.06 New Poster presentation at Sensorimotor circuits for limb control @ OIST 2024.01.31 New The 13th NIPS-EHUB-BRI joint symposium is held @ BRI. 2024.01.19 New Invited lecture at the Univ Tokyo. 2023.12.01 New We will join several meetings in this winter. 2023.11.15 New Misaki has joined our lab! 2023.11.11 New Invited talks and poster presentations in several meetings. 2023.09.15 New A review article (in Japanese): Autonomic dysfunction and neural circuit rewiring in spinal cord injury. Ueno M. The Autonom Nerv Sys 60(3): 110-114, 2023 (in Japanese) 2023.09.04 New Sou has joined our lab! 2023.08.31 New Presentation at the "iPlasticity" summer meeting. 2023.08.09 New Shintaro's paper in Acta Neuropathologica: TDP-43 differentially propagates to induce antero- and retrograde degeneration in the corticospinal circuits in mouse focal ALS models. Tsuboguchi S, Nakamura Y, Ishihara T, Kato T, Sato T, Koyama A, Mori H, Koike Y, Onodera O, Ueno M. Acta Neuropathol 2023, in press 2023.07.25 New We present posters in the 46th Annual Meeting of the Japan Neuroscience Society (Toki, Yuka, Shintaro, Shoji, and Kohei @ Sendai). 2023.07.22 New Presentation at the 63th Niigata biochemistry meeting (@ Niigata). 2023.07.20 New A new paper in collaboration: Voluntary running restores age-related loss of neural repair abilities and circadian rhythms after brain injury. Tanaka T, Ura H, Maeda T, Yanagita N, Mitsugi K, Koki H, Ueno M. J Phys Ther Fund. 2023 in press (in Japanese) 2023.07.20 New Inoue T. The exercise to support brain health. Noeken column (in Japanese) 2023.07.19 New Masamichi has joined our lab! 2023.07.14 New Talk at the 3rd meeting of homeodynamics (@ Kyoto). 2023.04.24 New Sicong has joined our lab! 2023.04.13 New Talk at the Partnership Symposium between DANDRITE, Aarhus University and BRI 2023.04.03 New Takanobu has joined our lab! 2023.03.31 New A review article (in Japanese): Cerebrospinal fluid-contacting neurons: spinal sensors of cerebrospinal fluid. Nakamura Y, Ueno M. The Cell 55(5): 32-6, 2023 2023.03.25 New Our work was introduced in eLife Insight. 2023.03.25 New A review article (in Japanese): Rewiring of corticospinal tract after central nervous system injuries. Inoue T, Ueno M. Jpn J Neuropsychol 39(1): 30-9, 2023 2023.03.24 New Seminar for high-school students in Niigata. 2023.02.21 New Yuka's paper in eLife: Cerebrospinal fluid-contacting neuron tracing reveals structural and functional connectivity for locomotion in the mouse spinal cord. Nakamura Y, Kurabe M, Matsumoto M, Sato T, Miyashita S, Hoshina K, Kamiya Y, Tainaka K, Matsuzawa H, Ohno N, Ueno M. eLife 12: e83108, 2023 2023.02.09 New Taka's paper. Temporal dynamics of brain BDNF expression following a single bout of exercise: A bioluminescence imaging study. Inoue T, Ikegami R, Takamatsu Y, Fukuchi M, Haga S, Ozaki M, Maejima H. Neurosci Lett 799: 137120, 2023 2023.02.03 New Presentation at the 12th NIPS-BRI-EHUB Joint Symposium 2023.01.17 New Satoshi's interview in BRI website. 2023.01.11 New Poster presentation at the IRCN-iPlasticity International Symposium (@ Tokyo). 2023.01.06 New Invited lecture at the Univ Tokyo. 2022.12.05 New Kohei's interview in BRI website. 2022.11.18 New Invited talk at iPlasticity online meeting. 2022.11.04 New A new paper in collaboration: Nakata S, Murai J, Okada M, Takahashi H, Findlay TH, Malebranche K, Parthasarathy A, Miyashita S, Gabdulkhaev R, Benkimoun I, Druillennec S, Chabi S, Hawkins E, Miyahara H, Tateishi K, Yamashita S, Yamada S, Saito T, On J, Jun Watanabe J, Tsukamoto Y, Yoshimura J, Oishi M, Nakano T, Imamura M, Imai C, Yamamoto T, Takeshima H, Sasaki AT, Rodriguez FJ, Nobusawa S, Varlet P, Pouponnot C, Osuka S, Pommier Y, Kakita A, Fujii Y, Raabe EH, Eberhart CG, Natsumeda M. Epigenetic upregulation of Schlafen11 renders WNT- and SHH- activated medulloblastomas sensitive to cisplatin. Neuro-oncology 2022 2022.10.07 New Invited talk at Nagoya University Grad School Medicine. 2022.10.01 New Taka got an excellence award from Japanese Society for Physical Therapy! 2022.09.09 New Invited talk at the 46th Annual Meeting of Neuropsychology Association of Japan (in Sapporo). 2022.09.05 New Yoshino has joined our lab! 2022.08.15 New Yuka's preprint on the study of CSF-contacting neurons is now on bioRxiv! 2022.08.02 New Presentation at the "iPlasticity" summer meeting. 2022.06.01 New A review article: Visualization of neuronal rewiring in brain and spinal cord injury. Sato T, Ueno M. Clin Neurosci. 40(6): 746-9, 2022 (in Japanese) 2022.04.08 New BRI movies on YouTube! 2022.04.01 New Takahiro and Kohei have joined our lab, welcome! 2022.03.24 New Invited talk at the 6th Chi no Hiroba Science Seminar. 2022.02.18 New Talk at the 11th NIPS-PRI-BRI symposium. 2022.02.18 New Satoshi's review paper: Transit amplifying progenitors in the cerebellum: similarities to and differences from transit amplifying cells in other brain regions and between species. Miyashita S, Hoshino M. Cells 11(4):726, 2022 2022.01.14 New Presentation at the "iPlasticity" meeting. 2021.12.01 New Toki was appointed to Associate professor in BRI!
