柿田先生

Members

Prof.
Akiyoshi KAKITA

Assoc. Prof.
Hiroshi SHIMIZU

Assist. Prof.
Asa NAKAHARA

Specially Appointed Assist. Prof.
Hideomi HAMASAKI

Specially Appointed Assist. Prof.
Ramil GABDULKHAEV

Mission

To provide the highest quality pathology services and scientific evidence focused on the advancement of developments in the field of neuropathology.

Vision

As an academic pathology department, we aim to deliver a high degree of professionalism in clinicopathological diagnostic services and neuropathology research, utilizing comprehensive and innovative approaches and building departmental competence to meet the needs of patients, institutions, and society.

Our approach will involve taking full advantage of opportunities to advance both the science and practice of neuropathology through individual and collaborative research, which hopefully will produce leading practitioners and researchers.

2023
Spinocerebellar ataxia (SCA) type 17-digenic TBP/STUB1 disease (SCA17-DI) has been recently segregated from SCA17, caused by digenic inheritance of two gene mutations - intermediate polyglutamine-encoding CAG/CAA repeat expansions in TBP (TBP41 − 49) and STUB1 heterozygosity - the former being associated with SCA17, and the latter with SCA48 and SCAR16 (autosomal recessive). We have reported clinicopathologic features of an autopsied patient with SCA17-DI and demonstrated that failure of polyubiquitin chain formation is associated with the pathogenicity of the mutant STUB1.

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